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Ken Itoh Selected Research

salvin

5/2015Carnosic acid attenuates apoptosis induced by amyloid-β 1-42 or 1-43 in SH-SY5Y human neuroblastoma cells.
2/2014Carnosic acid suppresses the production of amyloid-β 1-42 and 1-43 by inducing an α-secretase TACE/ADAM17 in U373MG human astrocytoma cells.
2/2013Carnosic acid suppresses the production of amyloid-β 1-42 by inducing the metalloprotease gene TACE/ADAM17 in SH-SY5Y human neuroblastoma cells.
8/2011Nrf2 regulates NGF mRNA induction by carnosic acid in T98G glioblastoma cells and normal human astrocytes.
4/2011Edaravone and carnosic acid synergistically enhance the expression of nerve growth factor in human astrocytes under hypoxia/reoxygenation.

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Ken Itoh Research Topics

Disease

15Neoplasms (Cancer)
07/2022 - 05/2002
10Carcinogenesis
07/2013 - 03/2002
9Inflammation (Inflammations)
11/2015 - 01/2004
5Alzheimer Disease (Alzheimer's Disease)
09/2021 - 02/2013
5Atherosclerosis
01/2020 - 03/2004
5Pneumonia (Pneumonitis)
12/2019 - 11/2005
5Carcinoma (Carcinomatosis)
07/2015 - 09/2004
4Cardiovascular Diseases (Cardiovascular Disease)
12/2021 - 01/2020
4Necrosis
01/2021 - 03/2006
4Fibrosis (Cirrhosis)
01/2020 - 03/2010
4Neuroblastoma
11/2016 - 02/2013
4Parkinson Disease (Parkinson's Disease)
02/2016 - 08/2010
4Lewy Body Disease (Lewy Body Dementia)
02/2016 - 08/2010
3Urinary Bladder Neoplasms (Bladder Cancer)
07/2022 - 03/2010
3Neurodegenerative Diseases (Neurodegenerative Disease)
09/2021 - 09/2015
3Astrocytoma (Pilocytic Astrocytoma)
12/2020 - 02/2014
3Dementia (Dementias)
02/2016 - 10/2011
3Hepatocellular Carcinoma (Hepatoma)
05/2014 - 11/2003
2Hearing Loss (Hearing Impairment)
06/2022 - 01/2020
2Starvation
03/2022 - 01/2020
2Body Weight (Weight, Body)
03/2022 - 02/2008
2Ischemia
08/2010 - 02/2008
2Acquired Immunodeficiency Syndrome (AIDS)
06/2007 - 06/2005
2Emphysema
12/2005 - 11/2005
1Obesity
10/2022
1Urologic Diseases (Urinary Tract Disease)
07/2022
1Renal Cell Carcinoma (Grawitz Tumor)
07/2022
1Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
07/2022
1Prostatic Hyperplasia (Benign Prostatic Hyperplasia)
07/2022
1Prostatic Neoplasms (Prostate Cancer)
07/2022
1Urinary Tract Infections (Urinary Tract Infection)
07/2022
1Uterine Cervical Neoplasms (Cancer of the Cervix)
12/2020
1Insulin Resistance
07/2020
1Nonsyndromic Deafness
01/2020
1Cardiomegaly (Heart Hypertrophy)
01/2020

Drug/Important Bio-Agent (IBA)

10Transcription Factors (Transcription Factor)IBA
12/2020 - 05/2002
10AntioxidantsIBA
04/2019 - 05/2002
9Proteins (Proteins, Gene)FDA Link
11/2016 - 09/2003
8EnzymesIBA
01/2020 - 05/2002
5salvinIBA
05/2015 - 04/2011
5IronIBA
08/2012 - 07/2004
4Biomarkers (Surrogate Marker)IBA
07/2022 - 10/2018
4Peptides (Polypeptides)IBA
09/2021 - 02/2013
4Pharmaceutical PreparationsIBA
09/2021 - 02/2008
4Messenger RNA (mRNA)IBA
01/2021 - 09/2009
4SynucleinsIBA
02/2016 - 10/2011
4DNA (Deoxyribonucleic Acid)IBA
10/2010 - 07/2005
3Nerve Growth Factor (NGF)IBA
04/2019 - 04/2011
3Proteasome Endopeptidase Complex (Proteasome)IBA
07/2015 - 07/2005
3Amyloid (Amyloid Fibrils)IBA
05/2015 - 02/2013
3Amyloid beta-PeptidesIBA
05/2015 - 02/2013
3SmokeIBA
05/2014 - 12/2005
2Mitochondrial DNA (mtDNA)IBA
06/2022 - 01/2020
2Amino AcidsFDA Link
03/2022 - 01/2020
2Carotenoids (Carotene)IBA
03/2021 - 07/2020
2Heme Oxygenase-1IBA
01/2021 - 07/2013
2Transforming Growth Factors (Transforming Growth Factor)IBA
01/2021 - 07/2013
2quinone (benzoquinone)IBA
01/2021 - 11/2016
2Amyloid Precursor Protein Secretases (beta-Secretase)IBA
02/2014 - 02/2013
2Endopeptidase K (Proteinase K)IBA
10/2011 - 08/2010
2Oxidants (Oxidizing Agents)IBA
03/2010 - 12/2005
2Uridine Diphosphate (UDP)IBA
03/2010 - 03/2006
2Peptide Hydrolases (Proteases)FDA Link
12/2005 - 11/2005
2CarrageenanIBA
06/2005 - 01/2004
2oltiprazIBA
09/2004 - 03/2003
2sulforaphaneIBA
11/2003 - 09/2003
1AmylasesFDA Link
10/2022
1Hormones (Hormone)IBA
07/2022
1Immunoglobulins (Immunoglobulin)IBA
07/2022
1Polysaccharides (Glycans)IBA
07/2022
1Liver GlycogenIBA
03/2022
1TamoxifenFDA LinkGeneric
03/2022
1Carrier Proteins (Binding Protein)IBA
03/2022
1Cysteine Proteases (Cysteine Protease)IBA
09/2021
1Cell-Penetrating PeptidesIBA
09/2021
1beta Carotene (Betacarotene)FDA Link
03/2021
1LuteinIBA
03/2021
1Oxidoreductases (Dehydrogenase)IBA
01/2021
1ChitinasesIBA
01/2021
1NAD (NADH)IBA
01/2021
1Superoxide Dismutase-1IBA
01/2021
1Interleukin-1beta (Interleukin 1 beta)IBA
01/2021
1CytokinesIBA
01/2021
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
01/2021
1Interleukin-4 Receptors (Interleukin 4 Receptor)IBA
01/2021
1TNF-Related Apoptosis-Inducing LigandIBA
12/2020
1Activating Transcription Factor 4IBA
12/2020
1HDL LipoproteinsIBA
07/2020
1HDL CholesterolIBA
07/2020
1Insulin (Novolin)FDA Link
07/2020
1Blood Glucose (Blood Sugar)IBA
07/2020
1Triglycerides (Triacylglycerol)IBA
07/2020
12-f)quinazoline-1,3-diamine N3- cyclopropyl- 7- ((4- (1- methylethyl)phenyl)methyl)- 7H- pyrrolo(3IBA
01/2020
1Eukaryotic Initiation Factor-2 (EIF 2)IBA
01/2020
1Indicators and Reagents (Reagents)IBA
01/2020
1ReninIBA
01/2020
1AminoglycosidesIBA
01/2020
1Anti-Bacterial Agents (Antibiotics)IBA
01/2020
1Zinc OxideFDA Link
12/2019

Therapy/Procedure

1Castration
07/2022